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Picture of the Day

How communication among cells affects development of multicellular tissue

Using a combination of computational modeling and experimental techniques, a research team has developed new information about how intercellular communication affects the differentiation of an embryonic stem cell colony over time. By providing new information about the role of communication among cells, the research could lead to a better understanding of how multicellular organoids form from colonies of independent cells. The information could lead to new methods for controlling how multicellular constructs develop, and that could have applications in regenerative medicine, pharmaceutical testing and other research areas. The goal is to control a system of cells like this to direct tissues to take on different phenotypes; to develop into different complex mixtures; and to self-assemble and emerge into very complicated structures. Scientists believe that the patterning of stem cell differentiation affects what kinds of cells will ultimately emerge from the differentiation process.

Visit Website | Image credit: Chad Glen/Georgia Tech