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Top Story

New type 1 diabetes therapy shows promise for long-term reversal in both humans, dogs

What if instead of daily insulin injections or wearing pumps, just getting a shot every few months could reverse Type 1 diabetes for you -- or your dog? It might take ushering in healthy pancreatic cells like a Trojan horse. The Trojan horse, in this case, would be collagen, a protein that the body already makes for building muscles, bones, skin and blood vessels. A collagen formulation mixed with pancreatic cells, developed by National Science Foundation-funded researchers, is the first minimally invasive therapy to successfully reverse Type 1 diabetes within 24 hours and maintain insulin independence for at least 90 days, a pre-clinical animal study shows. For diabetic pets, the next step is a pilot clinical study in dogs with naturally occurring Type 1 diabetes.

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