William Fenical of Scripps Institution of Oceanography at UC San Diego knows all about such drugs in the fight against cancer. But Fenical also knows that NPI-2358, or "Plinabulin," is different. Fenical and members of his laboratory discovered a microbe on the surface of a seaweed in the Bahamas that led to the development of Plinabulin, a synthetic derivative. Developed by Nereus Pharmaceuticals Inc., Plinabulin, now being tested in humans, is different from conventional cancer drugs: It targets established blood vessels in solid tumors such as lung cancer and tends to leave healthy cells alone.
Provided by the Scripps Institution of Oceanography