Picture of the Day

Stem cell resistance

A new study shows that adipose-derived human stem cells, which can become vital tissues such as bone, may be highly resistant to the common chemotherapy drug methotrexate (MTX). The preliminary finding from lab testing may prove significant because MTX causes bone tissue damage in many patients.

Ten days after treatment with a medically appropriate dose of MTX, adipose-derived stem cells, pictured here, survive while normal human fibroblasts are impaired. The inset shows untreated control cells.

Visit Website | Image credit: Darling lab/Brown University